Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274785 | 0.98 | PDE4A (0.52) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL20855314 | 0.94 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL6267186 | 0.84 | LMNA (0.62) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL1656749 | 0.84 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL1001815 | 0.84 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL3289378 | 0.82 | PDE4A (0.48) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL4395512 | 0.82 | PDE4A (0.59) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL1005420 | 0.82 | PDE4A (0.59) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL9355908 | 0.81 | PDE4A (0.57) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL3462304 | 0.81 | PDE4A (0.57) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753503-B1 | Process for preparation of xylaric acid and use thereof | ROQUETTE FRERES (FR) | 1999-06-09 | — | — | EP | disclosed |
| EP-0753503-A1 | Process for preparation of xylaric acid and use thereof | Roquette FrÀ¨res (FR) | 1997-01-15 | — | — | EP | disclosed |