Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853928 | 0.85 | ALDH1A1 (0.48) | PDGFRBPDGFRAALDH1A1KDM4EJAK2 | |
| SCHEMBL2851190 | 0.80 | ALDH1A1 (0.56) | PDGFRBPDGFRAALDH1A1KDM4EJAK2 | |
| SCHEMBL2853101 | 0.70 | KDM4E (0.40) | PDGFRBPDGFRAALDH1A1KDM4EJAK2 | |
| SCHEMBL2851463 | 0.69 | THRB (0.42) | PDGFRBPDGFRAALDH1A1MAP4K4GRIN2B | |
| SCHEMBL2853925 | 0.69 | PDGFRB (0.38) | PDGFRBPDGFRAALDH1A1KDM4EJAK2 | |
| SCHEMBL2849396 | 0.66 | CASP1 (0.53) | PDGFRBPDGFRAALDH1A1MAP4K4CHEK2 | |
| SCHEMBL4631895 | 0.65 | MAPK14 (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL2853181 | 0.64 | ALDH1A1 (0.38) | PDGFRBPDGFRAALDH1A1KDM4EMAP4K4 | |
| SCHEMBL1744640 | 0.63 | PIK3CD (0.52) | PDGFRBPDGFRAMAP4K4MEN1KMT2A | |
| SCHEMBL2851692 | 0.63 | ERN1 (0.51) | PDGFRBPDGFRAALDH1A1MAP4K4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924558-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007032016-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | disclosed |