Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 7/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 10/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904596 | 0.85 | EPHX2 (0.44) | MMP3POLBCTDSP1MEN1KMT2A | |
| SCHEMBL4907951 | 0.81 | MAPT (0.47) | MMP9 | |
| SCHEMBL4906479 | 0.79 | CTSS (0.45) | MMP3MMP9MMP1MEN1KMT2A | |
| SCHEMBL4814646 | 0.77 | POLB (0.50) | MMP3MMP9MMP1POLBCTDSP1 | |
| SCHEMBL4814666 | 0.77 | POLB (0.50) | MMP3MMP9MMP1POLBCTDSP1 | |
| SCHEMBL14104859 | 0.75 | CTSK (0.52) | MMP3MMP9MMP1POLBCTDSP1 | |
| SCHEMBL16964615 | 0.73 | POLB (0.59) | MMP9POLBCTDSP1MEN1KMT2A | |
| SCHEMBL26089233 | 0.72 | POLB (0.46) | MMP3POLBCTDSP1MEN1KMT2A | |
| SCHEMBL26089237 | 0.72 | POLB (0.46) | MMP3POLBCTDSP1MEN1KMT2A | |
| SCHEMBL27518632 | 0.71 | POLB (0.57) | MMP3MMP9MMP1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058333-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | CATALANO JOHN G | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058333-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | CTSK, CTSS, CTSE | MMP3 191/4885MMP9 633/4885MMP1 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.