SCHEMBL4897261

SCHEMBL4897261

CCn1ccnc1CC[Si](OC)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
ADRA2B P18089 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAPT P10636 1/20 0.36
ABCB11 O95342 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 2/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2C P18825 1/20 0.35
LMNA P02545 1/20 0.34
PKM P14618 1/20 0.34
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4888405 0.90 ALDH1A1 (0.35) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
SCHEMBL4895866 0.85 CYP1A2 (0.35) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
SCHEMBL4897020 0.82 ADRA2B (0.38) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
SCHEMBL30481688 0.79 CYP1A2 (0.38) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
SCHEMBL4226466 0.77 KCNH2 (0.46) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
Iodide SCHEMBL16164202 0.76 KCNH2 (0.44) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
SCHEMBL4897504 0.76 KMT2A (0.34) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6
Bromide SCHEMBL23581802 0.75 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP3A4CYP2C19KMT2A
SCHEMBL4898433 0.75 MC4R (0.35)
SCHEMBL14402534 0.74 GABRA1 (0.41) ALDH1A1ADRA2BCYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274305-A1 Liquid Crystal Sealant and Liquid Crystal Display Cell Utilizing the Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
EP-1780587-A1 LIQUID CRYSTAL SEALANT AND LIQUID CRYSTAL DISPLAY CELL UTILIZING THE SAME Nippon Kayaku Kabushiki Kaisha (JP) 2007-05-02 EP disclosed