Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511730 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL7966299 | 0.85 | KMT2A (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL3143396 | 0.85 | KMT2A (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL234681 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL7966302 | 0.85 | KMT2A (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL17359243 | 0.84 | TDP1 (0.63) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL50130 | 0.84 | TDP1 (0.63) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL17356545 | 0.84 | TDP1 (0.63) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL15246778 | 0.84 | TDP1 (0.63) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL14388708 | 0.84 | TDP1 (0.63) | ALDH1A1TP53TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109517082-B | Non-long linear chain alkyl hydrophobically modified hydroxyethyl guar gum thickener and preparation method thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-103013945-A | Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant | UNIV EAST CHINA SCIENCE & TECH | 2013-04-03 | — | — | CN | claimed |
| CN-116180172-A | Copper plating solution additive for increasing regional polarization resistance, copper plating solution and application thereof | 广东硕成科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-109517082-B | Non-long linear chain alkyl hydrophobically modified hydroxyethyl guar gum thickener and preparation method thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-103013945-B | Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant | UNIV EAST CHINA SCIENCE & TECH | 2014-06-11 | — | — | CN | disclosed |
| CN-103013945-A | Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant | UNIV EAST CHINA SCIENCE & TECH | 2013-04-03 | — | — | CN | disclosed |
| US-20080255134-A1 | Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase | ARTESIAN THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| EP-1833480-A2 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | Artesian Therapeutics, Inc. (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006060122-A9 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS INC (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006060122-A2 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| EP-0576617-B1 | COMPOSITION AND METHOD CONTAINING OPTICALLY PURE (S) METOPROLOL | SEPRACOR INC (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0677291-A2 | Composition and method containing optically pure (S) metoprolol | SEPRACOR, INC. (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0576617-A1 | COMPOSITION AND METHOD CONTAINING OPTICALLY PURE (S) METOPROLOL. | SEPRACOR INC (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016197-A1 | COMPOSITION AND METHOD CONTAINING OPTICALLY PURE (S) METOPROLOL | SEPRACOR INC. (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0179386-B1 | 1,4-DIHYDROPYRIDINE HYDROXYAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL AGENTS | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |
| EP-0218068-A1 | Dihydropyridine-2-hydroxyamines, process for their preparation and their use in medicaments | BAYER AG (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0179386-A2 | 1,4-Dihydropyridine hydroxyamines, process for their preparation and their use as pharmaceutical agents | BAYER AG (DE) | 1986-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255134-A1 | Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase | ADRB3, PDE3A, ADRB1 | ALDH1A1 1034/4885TP53 4868/4885TSHR 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.