Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897316 | 0.92 | PYGL (0.39) | SCN9APYGLPYGMDPP4CCKBR | |
| SCHEMBL4893208 | 0.91 | CCKBR (0.36) | SCN9ADPP4CCKBR | |
| SCHEMBL4894329 | 0.84 | SCN9A (0.35) | SCN9ADPP4CCKBRRIPK1 | |
| SCHEMBL4897302 | 0.83 | RIPK1 (0.34) | SCN9ADPP4RIPK1 | |
| SCHEMBL4887286 | 0.83 | RIPK1 (0.37) | SCN9ADPP4CCKBRRIPK1 | |
| SCHEMBL14280842 | 0.82 | SCN9A (0.37) | SCN9APYGLPYGMDPP4RIPK1 | |
| SCHEMBL14280841 | 0.82 | DPP4 (0.44) | DPP4 | |
| SCHEMBL4897558 | 0.81 | SCN9A (0.35) | SCN9ADPP4CCKBR | |
| Hydrochloric Acid SCHEMBL4912801 | 0.81 | DPP4 (0.44) | DPP4 | |
| Hydrochloric Acid SCHEMBL4912792 | 0.81 | DPP4 (0.44) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | DPP4, DPP8, DPP3 | SCN9A 718/4885PYGL 1009/4885PYGM 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.