Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 8/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078320 | 0.96 | TACR1 (0.42) | TACR1FKBP4MMP3MMP1PSMB9 | |
| SCHEMBL3314831 | 0.88 | TACR1 (0.41) | TACR1FKBP4TRPV1MMP2HPGD | |
| SCHEMBL3513112 | 0.88 | FKBP4 (0.44) | TACR1FKBP4MMP3MMP1TRPV1 | |
| SCHEMBL366333 | 0.87 | TACR1 (0.51) | TACR1FKBP4PSMB9 | |
| SCHEMBL1088249 | 0.87 | TACR1 (0.41) | TACR1FKBP4MMP3MMP1TRPV1 | |
| SCHEMBL4824283 | 0.86 | PDF (0.43) | TACR1FKBP4 | |
| SCHEMBL3926322 | 0.86 | TACR1 (0.41) | TACR1FKBP4TRPV1MMP2HPGD | |
| SCHEMBL6044127 | 0.85 | TACR1 (0.49) | TACR1FKBP4PSMB9KMT2A | |
| SCHEMBL368075 | 0.84 | TACR1 (0.39) | TACR1FKBP4 | |
| SCHEMBL1087550 | 0.83 | TACR1 (0.43) | TACR1FKBP4MMP3MMP1PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080220499-A1 | NOVEL PROTEASE FOR INDUSTRIAL APPLICATIONS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-09-11 | — | — | US | disclosed |
| US-5780439-A | HYPOALLERGENIC, GLYCOPROTEIN-FREE OLIGOPEPTIDE MIXTURE | NOVARTIS NUTRITION AG (CH) | 1998-07-14 | — | — | US | disclosed |
| US-5212068-A | Genetic engineering, biosynthesis | SANKYO COMPANY LIMITED (JP) | 1993-05-18 | — | — | US | disclosed |
| US-4985361-A | GENETIC ENGINEERING | SANKYO COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0198645-B1 | HUMAN PANCREATIC ELASTASE | SANKYO COMPANY LIMITED (JP) | 1990-11-22 | — | — | EP | disclosed |
| EP-0198645-A1 | Human pancreatic elastase | SANKYO COMPANY LIMITED (JP) | 1986-10-22 | — | — | EP | disclosed |