Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257064 | 0.85 | CA2 (0.53) | CA2CA1G6PC1KMT2AALDH1A1 | |
| SCHEMBL4257061 | 0.85 | CA2 (0.53) | CA2CA1G6PC1KMT2AALDH1A1 | |
| SCHEMBL4891588 | 0.79 | CA2 (0.52) | CA2CA1G6PC1KMT2AALDH1A1 | |
| SCHEMBL16073014 | 0.79 | CA2 (0.52) | CA2CA1G6PC1KMT2AALDH1A1 | |
| SCHEMBL4900404 | 0.78 | ALDH1A1 (0.56) | G6PC1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL4254637 | 0.78 | G6PC1 (0.51) | CA2CA1G6PC1KMT2AALDH1A1 | |
| SCHEMBL4254642 | 0.78 | G6PC1 (0.51) | CA2CA1G6PC1KMT2AALDH1A1 | |
| SCHEMBL4252465 | 0.73 | G6PC1 (0.47) | CA2G6PC1KMT2AALDH1A1RAB9A | |
| SCHEMBL4255942 | 0.73 | G6PC1 (0.47) | CA2G6PC1KMT2AALDH1A1RAB9A | |
| SCHEMBL15328915 | 0.71 | KDM4E (0.50) | CA2CA1G6PC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |