SCHEMBL4898415

SCHEMBL4898415

O=C1CCC(=O)O1.O=C1OC(=O)c2cccc1c2

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
GLA P06280 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGS2 P35354 1/20 0.33
TYMS P04818 1/20 0.32
PSMB8 P28062 1/20 0.31
PLA2G10 O15496 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27505 0.85 ALOX15 (0.43) ALOX15TDP1PTGS2TYMSPSMB8
SCHEMBL21173956 0.83 MEN1 (0.42) CYP1A2CYP2C9CYP2C19ALOX15TDP1
SCHEMBL21173954 0.78 CA12 (0.41) KDM4EHPGDALOX15TDP1PTGS2
Phthalic Anhydride SCHEMBL11139492 0.74 TDP1 (0.67) TSHRKDM4ECYP1A2CYP2C9HPGD
Ethylene Glycol SCHEMBL7060627 0.74 MEN1 (0.36) KDM4ECYP1A2GLAHPGDALOX15
SCHEMBL8848157 0.73 ALDH1A1 (0.33) KDM4EHPGDHSD17B10ALOX15TDP1
SCHEMBL10445528 0.71 NTSR1 (0.41) ALOX15TDP1PTGS2TYMSPSMB8
Phthalic Anhydride SCHEMBL8030359 0.71 TDP1 (0.70) TSHRKDM4ECYP1A2GLACYP2C9
SCHEMBL16123 0.71
SCHEMBL1333224 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7417102-B2 Pigment dispersant, method of making coating compositions, and coating compositions BASF CORPORATION (US) 2008-08-26 US disclosed
US-20070062412-A1 PIGMENT DISPERSANT, METHOD OF MAKING COATING COMPOSITIONS, AND COATING COMPOSITIONS BASF CORPORATION (US) 2007-03-22 US disclosed