Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7515523 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28310034 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5097554 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28061916 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5488857 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28085285 | 0.94 | — | — | |
| Bicarbonate SCHEMBL30589 | 0.94 | — | — | |
| Bicarbonate SCHEMBL6673355 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17868581 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28085287 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080553-A | High-temperature-resistant sealing rubber material and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-115349576-A | Solid powdery water-soluble compound acidifier as well as preparation method and application thereof | 天宝动物营养科技股份有限公司 | 2022-11-18 | — | — | CN | claimed |
| US-20070281056-A1 | Premixes, Flour Enriched With Same, Mineral Supplemented Foodstuffs And Methods Of Manufacture Thereof | NUTRACEUTICALS LIMITED (GB) | 2007-12-06 | — | — | US | claimed |
| EP-1791433-A2 | PREMIX COMPRISING CALCIUM AND VITAMIN D, FLOUR ENRICHED WITH SAME UND BREAD PRODUCT THEREFROM | Nutraceuticals Limited (GB) | 2007-06-06 | — | — | EP | claimed |
| WO-2006016170-A2 | PREMIXES, FLOUR ENRICHED WITH SAME, MINERAL SUPPLEMENTED FOODSTUFF AND METHODS OF MANUFACTURE THEREOF | NUTRACEUTICALS LIMITED (GB) | 2006-02-16 | — | — | WO | claimed |
| CN-1543434-A | Compositions and methods for treating cells and plants | 沃尔特・H・冉克斯 | 2004-11-03 | — | — | CN | claimed |
| US-5290844-A | Water-swellable adhesive water stop | C. I. KASEI CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| EP-0410669-B1 | WATER-SWELLABLE ADHESIVE WATER STOP | C.I. KASEI CO., LTD (JP) | 1993-04-21 | — | — | EP | claimed |
| EP-0410669-A2 | Water-swellable adhesive water stop | C.I. KASEI CO., LTD (JP) | 1991-01-30 | — | — | EP | claimed |
| US-12486169-B1 | CaB2O4/PbO/CuO/Pb3O4/PbB2O4/Pb4O(BO3)2 nanocomposite material and method of making | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2025-12-02 | — | — | US | disclosed |
| US-12454461-B1 | Fabrication of CaB2O4/Co3(BO3)2/PbO2/Co3O4 nanocomposite material using Pechini sol-gel method | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2025-10-28 | — | — | US | disclosed |
| US-12357962-B1 | Fabrication of Ca3Co4O9/MgO nanocomposite materials using pechini sol-gel method | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2025-07-15 | — | — | US | disclosed |
| US-20240197693-A1 | METHODS OF ADMINISTERING ANTI-FIBROTIC THERAPY | GENENTECH, INC. | 2024-06-20 | — | — | US | disclosed |
| US-11925624-B2 | Methods of administering anti-fibrotic therapy | GENENTECH, INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-6184414-B1 | EXTRACTION OF THE BUTYRIC ACID, OBTAINED BY THE CYANOHYDRIN REACTION WITH METHYLMERCAPTOPROPIONALDEHYDE AND ACIDOLYSIS, WITH AN INERT SOLVENT NON-MISCIBLE OR PARTIALLY MISCIBLE WITH WATER TO SEPARATE ORGANIC PRODUCTS AND AMMONIUM SALTS; FEEDS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 2001-02-06 | — | — | US | disclosed |
| EP-0405363-B1 | Heat-sensitive recording material | NEW OJI PAPER CO LTD (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5290844-A | Water-swellable adhesive water stop | C. I. KASEI CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0410669-B1 | WATER-SWELLABLE ADHESIVE WATER STOP | C.I. KASEI CO., LTD (JP) | 1993-04-21 | — | — | EP | disclosed |
| EP-0410669-A2 | Water-swellable adhesive water stop | C.I. KASEI CO., LTD (JP) | 1991-01-30 | — | — | EP | disclosed |
| US-4493776-A | HYDROCARBON OIL, OVERBASED DETERGENT, ASHLESS DISPERSANT, AND HYDROXYETHER COMPOUND | SHELL OIL COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197693-A1 | METHODS OF ADMINISTERING ANTI-FIBROTIC THERAPY | MMP1, MMP8, COL2A1 | CA4 3052/4885CA1 4376/4885FAHD1 2605/4885 |
| US-11925624-B2 | Methods of administering anti-fibrotic therapy | MMP1, MMP8, COL2A1 | CA4 3052/4885CA1 4376/4885FAHD1 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.