Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898671 | 1.00 | CYP2D6 (0.35) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL4892454 | 0.85 | CYP2D6 (0.33) | CYP2D6CYP2C19EPHX1 | |
| SCHEMBL4892460 | 0.85 | CYP2D6 (0.33) | CYP2D6CYP2C19EPHX1 | |
| SCHEMBL13989344 | 0.85 | CYP2D6 (0.33) | CYP2D6CYP2C19EPHX1 | |
| SCHEMBL4086594 | 0.79 | — | — | |
| SCHEMBL4086602 | 0.79 | — | — | |
| SCHEMBL4092392 | 0.75 | — | — | |
| SCHEMBL13940742 | 0.75 | — | — | |
| SCHEMBL16259082 | 0.75 | CYP2D6 (0.38) | CYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL4092401 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | GABRB1, GABBR2, GABRB2 | CYP2D6 1054/4885CYP2C19 467/4885MMP1 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.