Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910047 | 0.82 | ALDH1A1 (0.46) | ACHEALDH1A1KDM4EKMT2ADRD4 | |
| Hydrochloric Acid SCHEMBL4884319 | 0.81 | ALDH1A1 (0.45) | ACHEALDH1A1KDM4EKMT2ADRD4 | |
| Hydrochloric Acid SCHEMBL4912422 | 0.76 | LMNA (0.46) | ALDH1A1DRD2DRD3RAB9ALMNA | |
| SCHEMBL4901542 | 0.72 | STAT1 (0.48) | ACHEALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL1600111 | 0.72 | KMT2A (0.65) | ALDH1A1KDM4EKMT2ATSHRALOX15 | |
| SCHEMBL4905248 | 0.72 | LMNA (0.51) | ALDH1A1KMT2ATSHRSMN1; SMN2LMNA | |
| SCHEMBL4908538 | 0.70 | HPGD (0.36) | ACHEALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL10696789 | 0.69 | KMT2A (0.56) | ALDH1A1KDM4EKMT2ATSHRALOX15 | |
| Hydrochloric Acid SCHEMBL4899154 | 0.69 | MAPT (0.39) | ALDH1A1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL4901811 | 0.68 | KDM4E (0.38) | ALDH1A1KDM4EKMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | TYMP, HPRT1, IMPDH1 | ACHE 4419/4885BACE1 3028/4885ALDH1A1 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.