Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4884319 | 0.99 | ALDH1A1 (0.45) | ALDH1A1KDM4EHTTMAPTABCB1 | |
| SCHEMBL4913227 | 0.85 | MAPT (0.40) | ALDH1A1HTTMAPTABCC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4899154 | 0.84 | MAPT (0.39) | ALDH1A1HTTMAPTABCC1SMN1; SMN2 | |
| SCHEMBL4910144 | 0.82 | NR3C1 (0.45) | ALDH1A1HTTMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4900174 | 0.82 | ACHE (0.47) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4900154 | 0.81 | NR3C1 (0.44) | ALDH1A1HTTMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4905049 | 0.80 | ABCB1 (0.45) | ALDH1A1KDM4EHTTMAPTABCB1 | |
| SCHEMBL4907107 | 0.79 | MAPT (0.48) | ALDH1A1KDM4EMAPTABCB1ABCC1 | |
| SCHEMBL4901771 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL4901811 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EHTTMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | TYMP, HPRT1, IMPDH1 | ALDH1A1 191/4885KDM4E 4316/4885HTT 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.