Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614062 | 0.92 | CYP2C19 (0.35) | MEN1CYP2C19KMT2ATSHR | |
| SCHEMBL16862683 | 0.76 | — | — | |
| SCHEMBL16932723 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL533185 | 0.75 | MEN1 (0.37) | MEN1CYP2C19KMT2A | |
| SCHEMBL366283 | 0.74 | CYP2C19 (0.62) | MEN1CYP2C19KMT2ATSHR | |
| SCHEMBL3312229 | 0.72 | — | — | |
| SCHEMBL3140397 | 0.72 | NISCH (0.34) | MEN1KMT2A | |
| SCHEMBL8338491 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL28919686 | 0.71 | — | — | |
| SCHEMBL9451016 | 0.70 | MEN1 (0.44) | MEN1CYP2C19KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258751-B1 | CONTROLLING WEEDS IN CROPS | ROHM AND HAAS COMPANY | 2001-07-10 | — | — | US | claimed |
| EP-1061075-A2 | Substituted triazoles, imidazoles and pyrazoles as herbicides | ROHM AND HAAS COMPANY (US) | 2000-12-20 | — | — | EP | claimed |
| US-6107485-A | High pressure process to produce 2-aryl-3-substituted pyrimidione herbicides | ROHM AND HAAS COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| US-6054582-A | Process for pyrimidinone compounds | ROHM AND HAAS COMPANY (US) | 2000-04-25 | — | — | US | claimed |
| US-6051710-A | USEFUL INTERMEDIATES IN THE PREPARATION OF PYRIMIDINONES | ROHM AND HAAS COMPANY (US) | 2000-04-18 | — | — | US | claimed |
| US-5889184-A | Process for pyrimidinone compounds | PRINCETON UNIVERSITY (US) | 1999-03-30 | — | — | US | claimed |
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | claimed |
| US-5723414-A | APPLYING TO WEEDS | ROHM AND HAAS COMPANY (US) | 1998-03-03 | — | — | US | claimed |
| EP-0812832-A1 | Improved process for pyrimidinone compounds | ROHM AND HAAS COMPANY (US) | 1997-12-17 | — | — | EP | claimed |
| CN-1162598-A | Improved process for pyrimidinone compounds | UNIV PRINCETON (US) | 1997-10-22 | — | — | CN | claimed |
| CN-1141292-A | 2-aryl-5,6-dihydropyrimidinones and herbicidal use thereof | ROHM & HAAS (US) | 1997-01-29 | — | — | CN | claimed |
| EP-0579424-B1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0733622-A1 | 2-Aryl-5,6-dihydropyrimidinones and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-09-25 | — | — | EP | claimed |
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | claimed |
| CN-1109879-A | 2-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1995-10-11 | — | — | CN | claimed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | claimed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | claimed |
| CN-1084165-A | 2-Arylpyrimidines and weeding thereof are used | ROHM & HAAS (US) | 1994-03-23 | — | — | CN | claimed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | claimed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | claimed |