SCHEMBL4900638

SCHEMBL4900638

CC(O)N1CCOC(=O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
PIK3CD O00329 2/20 0.35
KCNJ1 P48048 4/20 0.31
KCNH2 Q12809 4/20 0.31
ACHE P22303 1/20 0.31
SSTR1 P30872 1/20 0.31
SLC6A4 P31645 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12706204 0.83 KDM4E (0.41) KDM4EPIK3CD
SCHEMBL149338 0.79
SCHEMBL16044897 0.79
SCHEMBL11486224 0.76 KDM4E (0.36) KDM4EPIK3CD
SCHEMBL12129103 0.69 KDM4E (0.37) KDM4EPIK3CD
SCHEMBL1031882 0.69
SCHEMBL4337347 0.69 HSD11B1 (0.36) KDM4E
Acrylic Acid SCHEMBL9444086 0.68 KDM4E (0.43) KDM4EPIK3CD
SCHEMBL12641147 0.68 KDM4E (0.39) KDM4EPIK3CD
SCHEMBL1717112 0.67 PIK3CD (0.53) KDM4EPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022023229-A1 CURABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM, AND METHODS OF FORMING THE SAME COVESTRO DEUTSCHLAND AG (DE) 2022-02-03 WO claimed
EP-3945101-A1 CURABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM, AND METHODS OF FORMING THE SAME Covestro Deutschland AG (DE) 2022-02-02 EP claimed
EP-3921312-A1 CURABLE COMPOSITIONS, PRODUCTS AND ARTICLES FORMED THEREFROM, AND METHODS OF FORMING THE SAME Covestro LLC (US) 2021-12-15 EP claimed
EP-3218423-B1 COMB POLYURETHANE DISPERSANTS HUNTSMAN PETROCHEMICAL LLC (US) 2021-01-06 EP claimed
US-10793667-B2 Curable compositions, products and articles formed therefrom, and methods of forming the same COVESTRO DEUTSCHLAND AG (DE) 2020-10-06 US claimed
US-20200255585-A1 CURABLE COMPOSITIONS, PRODUCTS AND ARTICLES FORMED THEREFROM, AND METHODS OF FORMING THE SAME COVESTRO LLC 2020-08-13 US claimed
WO-2020163464-A1 CURABLE COMPOSITIONS, PRODUCTS AND ARTICLES FORMED THEREFROM, AND METHODS OF FORMING THE SAME COVESTRO LLC (US) 2020-08-13 WO claimed
EP-3218423-A1 COMB POLYURETHANE DISPERSANTS Huntsman Petrochemical LLC (US) 2017-09-20 EP claimed
US-20170240756-A1 COMB POLYURETHANE DISPERSANTS HUNTSMAN PETROCHEMICAL LLC 2017-08-24 US claimed
WO-2016077147-A1 COMB POLYURETHANE DISPERSANTS HUNTSMAN PETROCHEMICAL LLC (US) 2016-05-19 WO claimed
US-7183360-B2 Method for crosslinking hydrogels with morpholine-2,3-diones BASF AKTIENGESELLSCHAFT (DE) 2007-02-27 US claimed
EP-1436335-B1 METHOD FOR CROSSLINKING HYDROGELS WITH MORPHOLINE-2,3-DIONES BASF AG (DE) 2005-01-26 EP claimed
US-20040231065-A1 Method for crosslinking hydrogels with morpholine-2,3-diones BASF AKTIENGESELLSCHAFT, A GERMAN CORPORATION (DE) 2004-11-25 US claimed
EP-1436335-A1 METHOD FOR CROSSLINKING HYDROGELS WITH MORPHOLINE-2,3-DIONES BASF AKTIENGESELLSCHAFT (DE) 2004-07-14 EP claimed
WO-2003031482-A1 METHOD FOR CROSSLINKING HYDROGELS WITH MORPHOLINE-2,3-DIONES BASF AKTIENGESELLSCHAFT (DE) 2003-04-17 WO claimed
WO-2022023229-A1 CURABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM, AND METHODS OF FORMING THE SAME COVESTRO DEUTSCHLAND AG (DE) 2022-02-03 WO disclosed
EP-3945101-A1 CURABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM, AND METHODS OF FORMING THE SAME Covestro Deutschland AG (DE) 2022-02-02 EP disclosed
EP-0371640-A1 A compound containing an oxamic acid group, a process for producing the compound, and a resin composition containing the compound NIPPON PAINT CO., LTD. (JP) 1990-06-06 EP disclosed
US-4184024-A Polyurethanes prepared from polyols from 2,3-morpholinediones TEXACO DEVELOPMENT CORP. (US) 1980-01-15 US disclosed
US-4118422-A Polyols from 2,3-morpholinediones TEXACO DEVELOPMENT CORP. (US) 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040231065-A1 Method for crosslinking hydrogels with morpholine-2,3-diones ADM2, COL1A1, MDN1 KDM4E 3022/4885PIK3CD 4599/4885KCNJ1 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.