Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768103 | 0.81 | RAB9A (0.58) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL30070767 | 0.80 | RAB9A (0.56) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL29543904 | 0.80 | RAB9A (0.64) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL26606001 | 0.79 | CA12 (0.61) | CA12CA9CA1CA2POLB | |
| SCHEMBL26606003 | 0.79 | CA12 (0.61) | CA12CA9CA1CA2POLB | |
| SCHEMBL9787706 | 0.79 | CA12 (0.65) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL5308606 | 0.78 | RAB9A (0.67) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL29544001 | 0.78 | RAB9A (0.67) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL3992539 | 0.78 | RAB9A (0.67) | ALDH1A1HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL30070592 | 0.78 | TDP1 (0.55) | ALDH1A1HPGDRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280920-A1 | Plasminogen Activator Inhibitor-1 Inhibitors | AMERICAN DIAGNOSTICA INC. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280920-A1 | Plasminogen Activator Inhibitor-1 Inhibitors | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 1116/4885HPGD 646/4885RAB9A 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.