Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988603 | 1.00 | POLB (0.38) | POLBACACBTP53TSHRPPARA | |
| SCHEMBL8988297 | 0.80 | POLB (0.42) | POLBTP53TSHRPPARAPPARG | |
| SCHEMBL4901097 | 0.78 | LMNA (0.44) | PPARAPPARGPLA2G4BKDM4E | |
| SCHEMBL13439646 | 0.75 | ALDH1A1 (0.40) | TSHRPPARAPPARGSMN1; SMN2 | |
| SCHEMBL8503705 | 0.74 | GRIK1 (0.36) | TP53TSHR | |
| SCHEMBL15301165 | 0.74 | ALDH1A1 (0.47) | POLBACACBPLA2G4BKDM4ECYP1A2 | |
| SCHEMBL11399171 | 0.73 | ALDH1A1 (0.50) | POLBTP53TSHRSMN1; SMN2 | |
| SCHEMBL11399168 | 0.73 | ALDH1A1 (0.50) | POLBTP53TSHRSMN1; SMN2 | |
| SCHEMBL10998787 | 0.73 | LTA4H (0.52) | PPARAPPARGSMN1; SMN2HIF1A | |
| SCHEMBL10998789 | 0.73 | LTA4H (0.52) | PPARAPPARGSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524187-B1 | POSITIVE WORKING RESIST COMPOSITIONS AND THEIR UTILITY IN DRY FILM PHOTORESISTS | DU PONT (US) | 1996-07-10 | — | — | EP | claimed |
| US-20080166666-A1 | POSITIVE IMAGEABLE THICK FILM COMPOSITION | ROACH DAVID HERBERT | 2008-07-10 | — | — | US | disclosed |