Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.62 |
| ▸ | BCR | P11274 | 3/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901153 | 0.85 | CAMKK2 (0.65) | ABL1BCRLCKCAMKK2PIK3CG | |
| SCHEMBL4901089 | 0.83 | MEN1 (0.62) | LCKPIK3CGDYRK1ACLK4CDK5 | |
| SCHEMBL4903542 | 0.82 | PIK3CG (0.54) | ABL1BCRCAMKK2PIK3CGMAPK8 | |
| SCHEMBL4897612 | 0.82 | JAK2 (0.56) | LCKPIK3CGDYRK1ACLK4CDK5 | |
| SCHEMBL2580846 | 0.81 | ABL1 (0.74) | ABL1BCRLCKCAMKK2PIK3CG | |
| SCHEMBL7601457 | 0.81 | ABL1 (0.78) | ABL1BCRLCKCAMKK2PIK3CG | |
| SCHEMBL4901211 | 0.81 | CDK5 (0.75) | ABL1BCRLCKPIK3CGDYRK1A | |
| SCHEMBL4786484 | 0.80 | ABL1 (0.77) | ABL1BCRLCKCAMKK2PIK3CG | |
| SCHEMBL3099819 | 0.80 | ABL1 (0.69) | ABL1BCRLCKCAMKK2PIK3CG | |
| Hydrochloric Acid SCHEMBL5205211 | 0.80 | ABL1 (0.76) | ABL1BCRLCKCAMKK2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | claimed |
| EP-1786781-A2 | PYRIMIDINE DERIVATIVES | GPC Biotech AG (DE) | 2007-05-23 | — | — | EP | claimed |
| WO-2006021458-A2 | PYRIMIDINE DERIVATIVES | GPC BIOTECH AG (DE) | 2006-03-02 | — | — | WO | claimed |
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | disclosed |
| EP-1786781-A2 | PYRIMIDINE DERIVATIVES | GPC Biotech AG (DE) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021458-A2 | PYRIMIDINE DERIVATIVES | GPC BIOTECH AG (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | TYMP, TDP1, PNP | ABL1 2843/4885BCR 2315/4885LCK 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.