Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phloroglucinol SCHEMBL9742017 | 0.89 | CA5A (0.67) | CA5ABACE1LMNACYP3A4MEN1 | |
| Phloroglucinol SCHEMBL4159496 | 0.86 | CA5A (0.63) | CA5ABACE1LMNACYP3A4MEN1 | |
| Phloroglucinol SCHEMBL10695302 | 0.86 | CA5A (0.63) | CA5ABACE1LMNACYP3A4MEN1 | |
| Phloroglucinol SCHEMBL2526824 | 0.83 | CA5A (0.60) | CA5ABACE1LMNACYP3A4MEN1 | |
| Resorcinol SCHEMBL10979680 | 0.82 | ALDH1A1 (0.67) | CA5ALMNACYP3A4KMT2ACA12 | |
| Hydroquinone SCHEMBL6451159 | 0.79 | CA1 (0.57) | CA5ALMNACYP3A4MEN1KMT2A | |
| Phloroglucinol SCHEMBL28617918 | 0.78 | ALDH1A1 (0.59) | CA5ABACE1LMNACYP3A4MEN1 | |
| SCHEMBL96189 | 0.78 | CA5A (1.00) | CA5ABACE1LMNACYP3A4MEN1 | |
| Phloroglucinol SCHEMBL22032286 | 0.76 | BACE1 (0.80) | CA5ABACE1LMNACYP3A4HPGD | |
| Orcinol SCHEMBL6749442 | 0.76 | ALDH1A1 (0.63) | CA5ABACE1LMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103179976-A | Glucagon superfamily peptides exhibiting g protein-coupled receptor activity | MARCADIA BIOTECH INC | 2013-06-26 | — | — | CN | claimed |
| CN-121574884-A | Lecaniella albopictus Jou-S14 and application thereof | 江苏海洋大学 | 2026-02-27 | — | — | CN | disclosed |
| CN-116836878-B | Pseudomonas fluorescens, microbial inoculum containing pseudomonas fluorescens, and preparation method and application thereof | 西南交通大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115193099-B | Method for extracting sphagnum active ingredient by using eutectic solvent | 广东省农业科学院环境园艺研究所 | 2023-11-07 | — | — | CN | disclosed |
| CN-117004667-A | Method for high-yield pyrazole triazine | 上海交通大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-116836878-A | Pseudomonas fluorescens, microbial inoculum containing pseudomonas fluorescens, and preparation method and application thereof | 西南交通大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-115193099-A | Method for extracting sphagnum moss active ingredient by using eutectic solvent | 广东省农业科学院环境园艺研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-103179976-A | Glucagon superfamily peptides exhibiting g protein-coupled receptor activity | MARCADIA BIOTECH INC | 2013-06-26 | — | — | CN | disclosed |
| US-20080090900-A1 | ANTIBIOTIC BUSHRIN | UNIVERSITY OF KARACHI (PK) | 2008-04-17 | — | — | US | disclosed |