Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.48 |
| ▸ | MECP2 | P51608 | 1/20 | 0.47 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.47 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.47 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.47 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902559 | 0.86 | ATM (0.45) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4901247 | 0.85 | GRM5 (0.48) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4902684 | 0.85 | KDR (0.42) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4902558 | 0.84 | TRPM8 (0.45) | GRM5ASIC3PTK2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL4900785 | 0.84 | GRM5 (0.50) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4899470 | 0.82 | GRM5 (0.50) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4899246 | 0.82 | RAB9A (0.48) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4892374 | 0.81 | GRM5 (0.53) | MEN1KMT2ANPC1RAB9AGRM5 | |
| Hydrochloric Acid SCHEMBL5309347 | 0.81 | RAB9A (0.47) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL2820941 | 0.81 | TRPM8 (0.68) | MEN1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | MEN1 2428/4885KMT2A 563/4885NPC1 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.