SCHEMBL4902432

SCHEMBL4902432

CC(C)c1c(OC(=O)c2ccc(O)cc2)cccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.50
ESR2 Q92731 6/20 0.50
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 5/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
JAK2 O60674 1/20 0.44
USP2 O75604 1/20 0.44
GAA P10253 1/20 0.44
ALOX15 P16050 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
KDM4E B2RXH2 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8778056 0.87 ESR1 (0.46) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL8766831 0.81 ESR1 (0.54) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL4846409 0.81 ESR1 (0.69) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL8768064 0.78 SENP1 (0.44) ESR1ESR2HSD17B10KMT2AGAA
SCHEMBL8768305 0.78 ESR1 (0.50) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL8767093 0.78 ESR1 (0.50) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL11417555 0.76 ESR1 (0.48) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL8778061 0.76 ESR1 (0.55) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL8768023 0.76 ESR1 (0.48) ESR1ESR2SLC6A3HSD17B10MAPT
SCHEMBL4124381 0.76 KDM4E (0.56) ESR1HSD17B10KMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080194403-A1 Laser Recording Thermally Sensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-08-14 US disclosed
EP-1707399-B1 LASER RECORDING TYPE HEAT-SENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2007-11-28 EP disclosed
US-20070099798-A1 Laser recording thermally sensitive recording medium NAGAI TOMOAKI 2007-05-03 US disclosed
EP-1398169-B1 LASER RECORDING TYPE HEAT SENSITIVE RECORDING ELEMENT JUJO PAPER CO LTD (JP) 2006-11-15 EP disclosed
EP-1707399-A1 LASER RECORDING TYPE HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2006-10-04 EP disclosed
US-20040171485-A1 Laser recording type heat sensitive recording element NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-09-02 US disclosed
EP-1398169-A1 LASER RECORDING TYPE HEAT SENSITIVE RECORDING ELEMENT Nippon Paper Industries Co., Ltd. (JP) 2004-03-17 EP disclosed
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed