SCHEMBL4846409

SCHEMBL4846409

O=C(Oc1ccccc1C(=O)O)c1ccc(O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.69
ESR2 Q92731 3/20 0.69
HSD17B10 Q99714 7/20 0.65
KDM4E B2RXH2 7/20 0.65
HPGD P15428 5/20 0.65
ALDH1A1 P00352 3/20 0.65
LMNA P02545 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
SLC6A3 Q01959 1/20 0.58
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
HMGB1 P09429 1/20 0.56
TSHR P16473 1/20 0.56
GGT1 P19440 1/20 0.56
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
BLM P54132 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11280439 0.93 KDM4E (0.68) ESR1ESR2HSD17B10KDM4EHPGD
Ethylbenzene SCHEMBL8778067 0.90 ESR1 (0.57) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL11273464 0.89 KDM4E (0.64) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL30505635 0.89 SLC6A3 (0.71) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL1979275 0.89 SLC6A3 (0.71) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL8777320 0.87 SLC6A3 (0.69) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL28263594 0.86 HSD17B10 (0.72) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL5162031 0.85 KMT2A (0.63) ESR1ESR2HSD17B10LMNASLC6A3
SCHEMBL5286893 0.85 CES2 (0.59) ESR1ESR2HSD17B10KDM4EHPGD
SCHEMBL7769807 0.85 ALDH1A1 (0.62) ESR1ESR2HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325231-B1 Heat-sensitive recording material JUJO PAPER CO LTD (JP) 1994-06-22 EP claimed
EP-0307836-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO PAPER CO., LTD. (JP) 1993-04-28 EP claimed
WO-2023101266-A1 POLYMER ELECTROLYTE MEMBRANE, FABRICATION METHOD THEREFOR, AND ELECTROCHEMICAL DEVICE COMPRISING SAME 코오롱인더스트리 주식회사 2023-06-08 WO disclosed
CN-110799345-B Tamper-resistant media for thermal printing 欧米亚国际集团 2022-04-19 CN disclosed
US-9040559-B2 BETA2-adrenoceptor agonists NOVARTIS AG (CH) 2015-05-26 US disclosed
US-20140343091-A1 BETA2-ADRENOCEPTOR AGONISTS NOVARTIS AG (CH) 2014-11-20 US disclosed
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-2146957-B1 QUATERNARY AMMONIUM COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS THERAVANCE INC (US) 2013-06-12 EP disclosed
US-7465694-B2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-12-16 US disclosed
US-7378374-B2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-05-27 US disclosed
US-20070265163-A1 Thermally Sensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2007-11-15 US disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed
EP-0693386-A1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-01-24 EP disclosed
US-5322831-A Color developers, chromogenic dye, stabilizer and sensitizer JUJO PAPER CO., LTD. (JP) 1994-06-21 US disclosed
EP-0559386-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-09-08 EP disclosed
US-5194466-A Stabilizers for heat, light and oxidation in polymers CIBA-GEIGY CORPORATION (US) 1993-03-16 US disclosed
US-5171855-A Photostability, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-12-15 US disclosed
EP-0399953-A2 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-11-28 EP disclosed
EP-0395584-A2 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-10-31 EP disclosed
US-4444844-A LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY RICOH CO., LTD. (JP) 1984-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343091-A1 BETA2-ADRENOCEPTOR AGONISTS ADRB2, ADRB1, ADRA2A ESR1 681/4885ESR2 142/4885HSD17B10 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.