SCHEMBL4902698

SCHEMBL4902698

C=CC(=O)c1ccc(C(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH5A1 P51649 1/20 0.57
ABAT P80404 1/20 0.57
AKT1 P31749 1/20 0.54
THRB P10828 8/20 0.52
THRA P10827 6/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MAPT P10636 2/20 0.48
MAPK1 P28482 2/20 0.48
EGFR P00533 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
JAK1 P23458 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4256312 0.82 ALDH5A1 (0.80) ALDH5A1ABATAKT1THRBTHRA
SCHEMBL1483380 0.81 ALDH1A1 (0.52) MEN1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL21600628 0.78 HDAC4 (0.51) THRBMEN1KMT2AKDM4EALDH1A1
SCHEMBL8844786 0.78 CYP2C9 (0.47) MEN1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL13305823 0.77 AKT1 (0.52) ALDH5A1ABATAKT1THRBMEN1
SCHEMBL7821842 0.76 ALDH1A1 (0.63) THRBTHRAMEN1KMT2AKDM4E
SCHEMBL7821843 0.76 ALDH1A1 (0.63) THRBTHRAMEN1KMT2AKDM4E
SCHEMBL28369537 0.76 HDAC4 (0.47) MEN1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL27952317 0.76 AKT1 (0.46) ALDH5A1ABATAKT1THRBTHRA
SCHEMBL1531083 0.76 CYP2C9 (0.53) MEN1KMT2AKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109963824-B Interlayer film for laminated glass, method for producing interlayer film for laminated glass, and laminated glass 积水化学工业株式会社 2022-09-16 CN disclosed
CN-111868578-A Light control body and light control window glass 积水化学工业株式会社 2020-10-30 CN disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed