Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720046 | 0.80 | MEN1 (0.47) | CYP2C9USP5HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1483380 | 0.79 | ALDH1A1 (0.52) | CYP2C9USP5HDAC4HDAC1HTT | |
| SCHEMBL13783625 | 0.78 | NFE2L2 (0.69) | CYP2C9USP5HDAC4HDAC1SMN1; SMN2 | |
| SCHEMBL4902698 | 0.78 | ALDH5A1 (0.57) | CYP2C9USP5HDAC4HDAC1HTT | |
| SCHEMBL8844390 | 0.77 | ALDH1A1 (0.64) | HTTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL4421107 | 0.77 | ALDH5A1 (0.56) | CYP2C9HTTLMNAALDH1A1MAPT | |
| SCHEMBL182327 | 0.76 | CYP2C9 (0.55) | CYP2C9USP5HTTSMN1; SMN2LMNA | |
| SCHEMBL21600628 | 0.76 | HDAC4 (0.51) | CYP2C9USP5HDAC4HDAC1HTT | |
| SCHEMBL12895032 | 0.76 | CYP2C9 (0.47) | CYP2C9USP5HTTSMN1; SMN2LMNA | |
| SCHEMBL19024320 | 0.75 | MAPT (0.66) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048279-A1 | AGENTS WITH ANTIFUNGAL ACTIVITY AND METHODS OF USE THEREOF | UNIVERSITY OF ALBERTA (US) | 1997-12-24 | — | — | WO | claimed |