Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | IDE | P14735 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797323 | 0.92 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL11665810 | 0.87 | ITGB3 (0.57) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL19510090 | 0.82 | EPHX1 (0.43) | ITGB3ITGA2BPTGER4LMNAEPHX1 | |
| SCHEMBL18705948 | 0.79 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL9621834 | 0.79 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL2558286 | 0.79 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL25255061 | 0.77 | ITGB1 (0.40) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL9860838 | 0.76 | ITGB1 (0.37) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL2582193 | 0.76 | TDP1 (0.45) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| Ammonia Solution, Strong SCHEMBL11055628 | 0.75 | ITGB1 (0.36) | ITGB1ITGA5ITGB3ITGA2BITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085968-A1 | Moulding Compound Comprising Polyoxymethylene And Zeolite | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-10 | — | — | US | disclosed |