Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.59 |
| ▸ | BCR | P11274 | 3/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.59 |
| ▸ | JAK2 | O60674 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899247 | 0.90 | ABL1 (0.73) | ABL1PDGFRBBCRPDGFRAJAK2 | |
| SCHEMBL4899326 | 0.89 | PDGFRB (0.56) | ABL1PDGFRBBCRPDGFRAJAK2 | |
| SCHEMBL4903437 | 0.87 | PDGFRA (0.73) | ABL1PDGFRBBCRPDGFRAEGFR | |
| SCHEMBL4899630 | 0.85 | ABL1 (0.64) | ABL1PDGFRBBCRPDGFRAJAK2 | |
| SCHEMBL4903136 | 0.83 | PDGFRA (0.82) | ABL1PDGFRBBCRPDGFRAEGFR | |
| SCHEMBL7461995 | 0.83 | JAK2 (0.73) | JAK2SYKAURKAJAK3 | |
| SCHEMBL4897416 | 0.83 | TRPV1 (0.53) | ABL1SMN1; SMN2TRPV1 | |
| SCHEMBL4901565 | 0.83 | MEN1 (0.59) | JAK2ADORA3PRKCACYP3A4SYK | |
| SCHEMBL3123402 | 0.81 | ABL1 (0.74) | ABL1PDGFRBBCRPDGFRAJAK2 | |
| SCHEMBL4892485 | 0.81 | PRKCA (0.62) | ABL1PDGFRBBCRPDGFRAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | claimed |
| EP-1786781-A2 | PYRIMIDINE DERIVATIVES | GPC Biotech AG (DE) | 2007-05-23 | — | — | EP | claimed |
| WO-2006021458-A2 | PYRIMIDINE DERIVATIVES | GPC BIOTECH AG (DE) | 2006-03-02 | — | — | WO | claimed |
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | TYMP, TDP1, PNP | ABL1 2843/4885PDGFRB 299/4885BCR 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.