SCHEMBL4903429

SCHEMBL4903429

O=C(Nc1ccccc1)c1ccccc1N=Nc1ccccc1C(=O)Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
MEN1 O00255 7/20 0.61
KMT2A Q03164 7/20 0.61
HPGD P15428 4/20 0.61
KDM4E B2RXH2 4/20 0.61
LMNA P02545 1/20 0.61
TP53 P04637 1/20 0.61
HTT P42858 1/20 0.61
HSD17B10 Q99714 1/20 0.61
TDP1 Q9NUW8 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
RAB9A P51151 3/20 0.59
METAP2 P50579 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
ALOX12 P18054 1/20 0.58
CHRNB2 P17787 1/20 0.58
CHRNB4 P30926 1/20 0.58
CHRNA3 P32297 1/20 0.58
CHRNA4 P43681 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437231 0.83 ALDH1A1 (0.87) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL10768773 0.82 MEN1 (0.59) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL11266259 0.81 ALDH1A1 (0.83) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL11266257 0.81 ALDH1A1 (0.83) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL12386075 0.81 HPGD (0.68) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL7995215 0.81 MEN1 (0.57) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL45299 0.78 ALDH1A1 (1.00) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL1991348 0.78 ALDH1A1 (1.00) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL1017795 0.78 CYP3A4 (0.89) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL8458952 0.78 HPGD (0.57) ALDH1A1MEN1KMT2AHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080119643-A1 4,4'-Diazobenzanilide Dyestuffs LENNARTZ MICHAEL 2008-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119643-A1 4,4'-Diazobenzanilide Dyestuffs CYP4B1, TYR, DDT ALDH1A1 155/4885MEN1 3273/4885KMT2A 392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.