SCHEMBL4903450

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4901340	0.95	HRH3 (0.47)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL4900340	0.80	PDE3B (0.55)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL4903296	0.79	PDE3B (0.54)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL4890576	0.79	PDE3B (0.54)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL7325592	0.78	HRH3 (0.67)	PDE3BPDE3ARAB9AHPGDNPC1
	SCHEMBL7330591	0.78	PDE3B (0.47)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL8266841	0.78	PDE3B (0.53)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL8191155	0.77	PDE3B (0.61)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL7327893	0.77	PDE3B (0.52)	PDE4BPDE3BPDE3APDE4APDE4C
	SCHEMBL8267127	0.77	PDE3B (0.55)	PDE4BPDE3BPDE3APDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.