SCHEMBL490357

SCHEMBL490357

c1ccc2c(Nc3ccc4c(c3)c3ccccc3n4-c3cccc4ccccc34)cccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 1/20 0.49
ALDH1A1 P00352 3/20 0.49
CDC25B P30305 2/20 0.49
CYP3A4 P08684 2/20 0.49
HPGD P15428 2/20 0.49
TP53 P04637 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
ATM Q13315 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RAB9A P51151 2/20 0.44
DHFR P00374 1/20 0.42
LMNA P02545 2/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
SIRT3 Q9NTG7 1/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25044489 0.87 CDC25B (0.46) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL12698813 0.87 ALDH1A1 (0.44) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL296012 0.86 CDC25B (0.53) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL29907968 0.86 CDC25B (0.53) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL14580816 0.86 ALDH1A1 (0.46) ALDH1A1CYP3A4HPGDHSD17B10DHFR
SCHEMBL14580815 0.84 ALDH1A1 (0.37) ALDH1A1CDC25BCYP3A4HPGDTP53
SCHEMBL9912853 0.83 CDC25B (0.56) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL14580817 0.83 FADS1 (0.46) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL30257473 0.83 FADS1 (0.40) FADS1ALDH1A1CDC25BCYP3A4HPGD
SCHEMBL14580820 0.82 ATM (0.48) FADS1ALDH1A1CDC25BCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10079345-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-18 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
EP-2084123-B1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-08-27 EP disclosed
EP-2084123-B1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-08-27 EP disclosed
US-20130306941-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-21 US disclosed
US-20130306941-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-21 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
EP-2084123-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-08-05 EP disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
WO-2007015407-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL OBTAINED BY USING CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10079345-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 FADS1 1154/4885ALDH1A1 45/4885CDC25B 2424/4885
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 FADS1 1154/4885ALDH1A1 45/4885CDC25B 2424/4885
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative XPOT, XPO1, XPO7 FADS1 1154/4885ALDH1A1 45/4885CDC25B 2424/4885
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device CYP1A1, GRIA1, GNA11 FADS1 3943/4885ALDH1A1 316/4885CDC25B 4606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.