Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886469 | 0.84 | CXCR4 (0.63) | CXCR4KCNH2 | |
| SCHEMBL4885902 | 0.84 | CXCR4 (0.63) | CXCR4KCNH2 | |
| SCHEMBL4889563 | 0.84 | CXCR4 (0.63) | CXCR4KCNH2 | |
| SCHEMBL14067034 | 0.82 | CXCR4 (0.43) | CXCR4KCNH2 | |
| SCHEMBL4905253 | 0.79 | HTR6 (0.48) | CXCR4KCNH2 | |
| SCHEMBL4887173 | 0.78 | CXCR4 (0.61) | CXCR4KCNH2 | |
| SCHEMBL14067054 | 0.75 | CXCR4 (0.41) | CXCR4KCNH2 | |
| SCHEMBL4884787 | 0.75 | CXCR4 (0.60) | CXCR4KCNH2 | |
| SCHEMBL20851434 | 0.74 | CXCR4 (0.71) | CXCR4KCNH2 | |
| SCHEMBL20851437 | 0.74 | CXCR4 (0.71) | CXCR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214562-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-04 | — | — | US | claimed |
| US-20080214562-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-04 | — | — | US | disclosed |
| US-20080214562-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-04 | — | — | US | disclosed |
| US-20080214562-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214562-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | CXCR4 2/4885KCNH2 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.