Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906157 | 0.92 | ALDH1A1 (0.39) | GAAALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL14067541 | 0.89 | ALDH1A1 (0.45) | GAAALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL14067498 | 0.89 | KDM4E (0.37) | ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL4904664 | 0.88 | PDE3B (0.40) | ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL14076857 | 0.87 | ALDH1A1 (0.43) | GAAALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL4894901 | 0.86 | KDM4E (0.42) | GAAALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL4906705 | 0.86 | MEN1 (0.38) | — | |
| SCHEMBL4590173 | 0.85 | MCHR1 (0.37) | TSHR | |
| SCHEMBL4903775 | 0.85 | ALDH1A1 (0.41) | GAAALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL4927680 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EPDE3BPDE3ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214527-A1 | Hiv Integrase Inhibitors | SHIONOGI & CO. LTD (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214527-A1 | Hiv Integrase Inhibitors | API5, ING2, SAMHD1 | GAA 1159/4885ALDH1A1 2874/4885KDM4E 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.