Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903788 | 0.92 | GAA (0.40) | ALDH1A1GAAKDM4ETSHRMAPT | |
| SCHEMBL4896125 | 0.92 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAALOX15KDM4E | |
| SCHEMBL4590144 | 0.90 | HSD17B10 (0.39) | ALDH1A1SMN1; SMN2ALOX15KDM4EPIK3CA | |
| SCHEMBL14067541 | 0.88 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2GAAKDM4ETSHR | |
| SCHEMBL4904664 | 0.85 | PDE3B (0.40) | ALDH1A1KDM4E | |
| SCHEMBL14076857 | 0.85 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2GAAKDM4ETSHR | |
| SCHEMBL4906678 | 0.85 | KMT2A (0.42) | TSHRPIK3CAHPGD | |
| SCHEMBL4907817 | 0.85 | CNR2 (0.40) | KDM4EKCNH2TSHRPIK3CAHPGD | |
| SCHEMBL4894901 | 0.85 | KDM4E (0.42) | ALDH1A1SMN1; SMN2GAAKDM4EKCNH2 | |
| SCHEMBL14067498 | 0.84 | KDM4E (0.37) | ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214527-A1 | Hiv Integrase Inhibitors | SHIONOGI & CO. LTD (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214527-A1 | Hiv Integrase Inhibitors | API5, ING2, SAMHD1 | ALDH1A1 2874/4885SMN1; SMN2 4800/4885GAA 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.