Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9350965 | 0.99 | ELANE (0.50) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL14997833 | 0.99 | ELANE (0.50) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL29201825 | 0.94 | HTT (0.43) | ELANEHTTPOLBAPEX1TDP1 | |
| Bromide SCHEMBL2250534 | 0.90 | MEN1 (0.44) | HTTPOLBAPEX1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL166563 | 0.88 | MEN1 (0.45) | HTTPOLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL1476595 | 0.88 | MEN1 (0.45) | HTTPOLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL14999554 | 0.88 | ELANE (0.52) | ELANEHTTPOLBAPEX1TDP1 | |
| Hydrochloric Acid SCHEMBL6560373 | 0.87 | POLB (0.54) | ELANEHTTPOLBAPEX1TDP1 | |
| Fluoride Ion SCHEMBL14815797 | 0.87 | MEN1 (0.44) | HTTPOLBAPEX1TDP1ALDH1A1 | |
| Iodide SCHEMBL2252213 | 0.87 | MEN1 (0.44) | HTTPOLBAPEX1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193497-A1 | Hydrophilic Coating of a Water-Swellable Hydrophilic Matrix and an Anti-Microbial Polymer | COLOPLAST A/S (DK) | 2008-08-14 | — | — | US | claimed |
| EP-1740044-A1 | A HYDROPHILIC COATING OF A WATER-SWELLABLE HYDROPHILIC MATRIX AND AN ANTI-MICROBIAL POLYMER | COLOPLAST A/S (DK) | 2007-01-10 | — | — | EP | claimed |
| WO-2005104845-A1 | A HYDROPHILIC COATING OF A WATER-SWELLABLE HYDROPHILIC MATRIX AND AN ANTI-MICROBIAL POLYMER | COLOPLAST A/S (DK) | 2005-11-10 | — | — | WO | claimed |
| US-20040144657-A1 | Process for the surface-immobililzation of anti-microbial polymers by metal deposition | DEGUSSA AG (DE) | 2004-07-29 | — | — | US | claimed |
| WO-2003068316-A1 | COSMETIC FORMULATIONS THAT CONTAIN ANTIMICROBIAL POLYMERS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2003-08-21 | — | — | WO | claimed |
| EP-1293123-A1 | Biocidal formulations with sustained release | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2003-03-19 | — | — | EP | claimed |
| WO-2003014274-A1 | ANTIMICROBIAL CLEANING AGENT | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2003-02-20 | — | — | WO | claimed |
| EP-1277882-A2 | Microbicidal wall coverings | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2003-01-22 | — | — | EP | claimed |
| WO-2003003829-A1 | ANTIMICROBIAL FOAMED MATERIALS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2003-01-16 | — | — | WO | claimed |
| EP-1214367-A1 | COPOLYMERS OF ACRYLOYLOXYALKYLAMINO COMPOUNDS | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-06-19 | — | — | EP | claimed |
| WO-2001016193-A1 | COPOLYMERS OF ACRYLOYLOXYALKYLAMINO COMPOUNDS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2001-03-08 | — | — | WO | claimed |
| US-20130143056-A1 | PHOTO-VINYL LINKING AGENTS | SURMODICS, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20080193497-A1 | Hydrophilic Coating of a Water-Swellable Hydrophilic Matrix and an Anti-Microbial Polymer | COLOPLAST A/S (DK) | 2008-08-14 | — | — | US | disclosed |
| EP-1740044-A1 | A HYDROPHILIC COATING OF A WATER-SWELLABLE HYDROPHILIC MATRIX AND AN ANTI-MICROBIAL POLYMER | COLOPLAST A/S (DK) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005104845-A1 | A HYDROPHILIC COATING OF A WATER-SWELLABLE HYDROPHILIC MATRIX AND AN ANTI-MICROBIAL POLYMER | COLOPLAST A/S (DK) | 2005-11-10 | — | — | WO | disclosed |
| WO-2003014274-A1 | ANTIMICROBIAL CLEANING AGENT | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2003-02-20 | — | — | WO | disclosed |
| EP-1277882-A2 | Microbicidal wall coverings | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2003-01-22 | — | — | EP | disclosed |
| WO-2003003829-A1 | ANTIMICROBIAL FOAMED MATERIALS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2003-01-16 | — | — | WO | disclosed |
| EP-1214367-A1 | COPOLYMERS OF ACRYLOYLOXYALKYLAMINO COMPOUNDS | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016193-A1 | COPOLYMERS OF ACRYLOYLOXYALKYLAMINO COMPOUNDS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2001-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143056-A1 | PHOTO-VINYL LINKING AGENTS | PRXL2A, NOX4, PARP1 | ACHE 2349/4885CHRM2 2460/4885CHRM4 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.