Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901077 | 0.85 | APP (0.68) | APPCYP1A2STSGLAGAA | |
| SCHEMBL19627053 | 0.83 | APP (0.62) | APPCYP1A2CA2MAOB | |
| SCHEMBL31115697 | 0.79 | APP (1.00) | APPCYP1A2CA1MAOB | |
| SCHEMBL10038463 | 0.79 | APP (0.75) | APPCYP1A2 | |
| SCHEMBL563392 | 0.79 | APP (1.00) | APPCYP1A2CA1MAOB | |
| SCHEMBL1104925 | 0.77 | APP (0.80) | APPCYP1A2CA1 | |
| Ethoxyresorufin SCHEMBL31079400 | 0.76 | APP (1.00) | APPCYP1A2CA1GLA | |
| Ethoxyresorufin SCHEMBL104497 | 0.76 | APP (1.00) | APPCYP1A2CA1GLA | |
| SCHEMBL18932158 | 0.76 | APP (0.74) | APPCYP1A2GAA | |
| SCHEMBL18653522 | 0.76 | APP (0.70) | APPCYP1A2CA1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| WO-2009121247-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | WO | disclosed |
| US-20080286812-A1 | ALCOHOL OXIDASE-BASED ENZYME-LINKED IMMUNOSORBENT ASSAY | UNIVERSITY OF ST. THOMAS | 2008-11-20 | — | — | US | disclosed |
| US-20080286812-A1 | ALCOHOL OXIDASE-BASED ENZYME-LINKED IMMUNOSORBENT ASSAY | UNIVERSITY OF ST. THOMAS | 2008-11-20 | — | — | US | disclosed |
| US-20080286812-A1 | ALCOHOL OXIDASE-BASED ENZYME-LINKED IMMUNOSORBENT ASSAY | UNIVERSITY OF ST. THOMAS | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | ROS1, LPO, HMOX1 | APP 4089/4885CYP1A2 1456/4885HSD11B1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.