Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256851 | 0.93 | PDPK1 (0.39) | SIGMAR1IDO1 | |
| SCHEMBL1970744 | 0.91 | IDO1 (0.41) | SIGMAR1IDO1 | |
| SCHEMBL121704 | 0.83 | PDPK1 (0.43) | SIGMAR1IDO1 | |
| SCHEMBL815114 | 0.79 | MEN1 (0.38) | — | |
| SCHEMBL316316 | 0.75 | SRD5A1 (0.41) | SIGMAR1IDO1 | |
| SCHEMBL145977 | 0.75 | IDO1 (0.57) | SIGMAR1IDO1TSHRLMNA | |
| SCHEMBL29357487 | 0.75 | IDO1 (0.57) | SIGMAR1IDO1TSHRLMNA | |
| SCHEMBL4661810 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP | |
| SCHEMBL21924071 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP | |
| SCHEMBL30285859 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070968-A1 | Hexahydro-Cycloheptapyrazole Cannabinoid Modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070968-A1 | Hexahydro-Cycloheptapyrazole Cannabinoid Modulators | CNR2, CNR1, FAAH | SIGMAR1 662/4885IDO1 1290/4885EPHX1 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.