SCHEMBL4904944

SCHEMBL4904944

C=C(CS(C)(=O)=O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.39
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM2 Q14416 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543222 0.78 TSHR (0.32)
SCHEMBL31435 0.78 TET2 (0.37) TET2TET3TET1GRIK1GRIK2
SCHEMBL6030920 0.77 TET2 (0.35) TET2TET3TET1GRIK1GRIK2
SCHEMBL25832433 0.77
SCHEMBL2331153 0.76 TDP1 (0.41)
Itaconate SCHEMBL28431007 0.74 ALOX15 (0.60) TET2TET3TET1GRIK1GRIK2
SCHEMBL28251693 0.74 ALOX15 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL19543217 0.74 TDP1 (0.30)
SCHEMBL21986236 0.74 TBXAS1 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL190142 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332900-A Olefin compound and synthesis method thereof 华中科技大学 2023-06-27 CN claimed
EP-0831756-A1 BISPHOSPHONATE CEMENT COMPOSITION TO PREVENT ASEPTIC LOOSENING OF ORTHOPEDIC IMPLANT DEVICES Merck & Co., Inc. (US) 1998-04-01 EP claimed
WO-1996039107-A1 BISPHOSPHONATE CEMENT COMPOSITION TO PREVENT ASEPTIC LOOSENING OF ORTHOPEDIC IMPLANT DEVICES MERCK & CO., INC. (US) 1996-12-12 WO claimed
WO-2024249950-A1 FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN BIOMEA FUSION, INC. (US) 2024-12-05 WO disclosed
CN-116332900-A Olefin compound and synthesis method thereof 华中科技大学 2023-06-27 CN disclosed
EP-3007858-A1 LOW SURFACE ROUGHNESS POLISHING PAD Cabot Microelectronics Corporation (US) 2016-04-20 EP disclosed
EP-2953648-A1 NANOPARTICLES CONTAINING A TAXANE AND THEIR USE ANP Technologies, Inc. (US) 2015-12-16 EP disclosed
WO-2014200726-A1 LOW SURFACE ROUGHNESS POLISHING PAD CABOT MICROELECTRONICS CORPORATION (US) 2014-12-18 WO disclosed
EP-2648760-A2 SMART POLYMERIC NANOPARTICLES WHICH OVERCOME MULTIDRUG RESISTANCE TO CANCER CHEMOTHERAPEUTICS AND TREATMENT-RELATED SYSTEMIC TOXICITY The Johns Hopkins University (US) 2013-10-16 EP disclosed
WO-2012078831-A2 SMART POLYMERIC NANOPARTICLES WHICH OVERCOME MULTIDRUG RESISTANCE TO CANCER CHEMOTHERAPEUTICS AND TREATMENT-RELATED SYSTEMIC TOXICITY THE JOHNS HOPKINS UNIVERSITY (US) 2012-06-14 WO disclosed
US-20080103311-A1 Retroviral protease inhibitors PHARMACIA CORPORATION (US) 2008-05-01 US disclosed
EP-0558603-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-09-08 EP disclosed
EP-0558630-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-09-08 EP disclosed
EP-0558657-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-09-08 EP disclosed
EP-0554400-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-08-11 EP disclosed
WO-1992008700-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008701-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008688-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008699-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008698-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103311-A1 Retroviral protease inhibitors PREP, DNPEP, SERPINB1 TET2 3289/4885TET3 2733/4885TET1 2786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.