Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905778 | 1.00 | TRPA1 (0.47) | TRPA1ALDH1A1HTTPTGS2AKR1C2 | |
| SCHEMBL4905786 | 1.00 | TRPA1 (0.47) | TRPA1ALDH1A1HTTPTGS2AKR1C2 | |
| SCHEMBL14913574 | 0.86 | CYP1A2 (0.55) | TRPA1ALDH1A1HTTPTGS2AKR1C2 | |
| SCHEMBL16160152 | 0.85 | TRPA1 (0.51) | TRPA1ALDH1A1HTTPTGS2AKR1C2 | |
| SCHEMBL689448 | 0.82 | AKR1C3 (0.55) | ALDH1A1HTTAKR1C1AKR1C3MEN1 | |
| SCHEMBL22634102 | 0.82 | AKR1C3 (0.55) | ALDH1A1HTTAKR1C1AKR1C3MEN1 | |
| SCHEMBL490213 | 0.79 | THRB (0.50) | ALDH1A1AKR1C3CYP1A2MAPTNPSR1 | |
| SCHEMBL2647713 | 0.79 | MEN1 (0.49) | TRPA1ALDH1A1HTTPTGS2AKR1C2 | |
| SCHEMBL2647715 | 0.79 | MEN1 (0.49) | TRPA1ALDH1A1HTTPTGS2AKR1C2 | |
| SCHEMBL4906426 | 0.79 | THRB (0.50) | ALDH1A1AKR1C3CYP1A2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | AS3MT, PPA1, AGPS | TRPA1 3384/4885ALDH1A1 14/4885HTT 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.