Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910240 | 0.88 | SLC6A9 (0.66) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL4903243 | 0.88 | SLC6A9 (0.71) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL4914252 | 0.87 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL4911136 | 0.86 | SLC6A9 (0.63) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL4910182 | 0.86 | SLC6A9 (0.70) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL5040979 | 0.83 | SLC6A9 (0.86) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL2827218 | 0.83 | SLC6A9 (0.56) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL5042089 | 0.82 | SLC6A9 (1.00) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL5037809 | 0.82 | SLC6A9 (1.00) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL4429477 | 0.80 | SLC6A9 (0.75) | SLC6A9KCNH2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287455-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES | JOLIDON SYNESE | 2008-11-20 | — | — | US | disclosed |
| US-20080287455-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES | JOLIDON SYNESE | 2008-11-20 | — | — | US | disclosed |
| US-20080287455-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES | JOLIDON SYNESE | 2008-11-20 | — | — | US | disclosed |
| EP-1836178-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | F. Hoffmann-Roche AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006072435-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-07-13 | — | — | WO | disclosed |
| US-20060149062-A1 | Sulfanyl substituted phenyl methanones | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149062-A1 | Sulfanyl substituted phenyl methanones | SULT1A1, SULT2A1, SULT1E1 | SLC6A9 19/4885KCNH2 2426/4885SLC6A5 4/4885 |
| US-20080287455-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES | SULT1A1, SULT2A1, SULT1E1 | SLC6A9 19/4885KCNH2 2426/4885SLC6A5 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.