SCHEMBL4906207

SCHEMBL4906207

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1COC(F)C(F)F

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.31
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29014604 0.88 EPAS1 (0.31) EPAS1
SCHEMBL29014592 0.86
SCHEMBL1963115 0.86 HPD (0.31) HPDEPAS1
SCHEMBL29014626 0.84
SCHEMBL29014605 0.84
SCHEMBL5605375 0.84
SCHEMBL12269385 0.84 ALDH1A1 (0.33) HPD
SCHEMBL12770863 0.83 HPD (0.36) HPD
SCHEMBL29014612 0.83
SCHEMBL1961744 0.82 MAPT (0.33) HPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114585731-B Mutant hydroxyphenylpyruvate dioxygenase polypeptide, encoding gene and application thereof 北京大北农生物技术有限公司 2024-07-12 CN disclosed
CN-117986167-A Preparation method of cyclosulfamide 帕潘纳(北京)科技有限公司 2024-05-07 CN disclosed
CN-114854702-B Herbicide tolerance protein, coding gene and application thereof 北京大北农生物技术有限公司 2024-04-19 CN disclosed
CN-117837602-A Weeding composition and preparation method and application thereof 河北农信生物科技有限责任公司 2024-04-09 CN disclosed
CN-117822000-A Cyclosultone intermediate and electrooxidation preparation method thereof 厦门杰青连续流科技有限公司 2024-04-05 CN disclosed
CN-114560795-B Method for preparing cyclosulfamide 浙江先锋科技股份有限公司 2024-04-05 CN disclosed
CN-114680112-B Mixed weeding composition containing dicamba, cyclosulfamide and atrazine and application thereof 山东省联合农药工业有限公司 2023-11-07 CN disclosed
CN-113845451-B Method for preparing trione herbicide 沈阳中化农药化工研发有限公司 2023-07-14 CN disclosed
CN-112955011-B Compositions comprising pyridine carboxylic acid herbicides with photosystem II and optionally HPPD inhibitor herbicides 科迪华农业科技有限责任公司 2023-06-02 CN disclosed
CN-112087950-B Use of safeners for increasing the resistance of rice crops to herbicides 安道麦阿甘有限公司 2023-02-28 CN disclosed
US-20080269059-A1 PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE BAYER CROPSCIENCE AG (DE) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269059-A1 PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE CYC1, PYCR1, CBR3 HPD 115/4885EPAS1 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.