Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.61 |
| ▸ | BCHE | P06276 | 7/20 | 0.61 |
| ▸ | ACHE | P22303 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634965 | 0.88 | BCHE (0.66) | BACE1BCHEACHE | |
| SCHEMBL4902967 | 0.80 | ACHE (0.64) | BACE1BCHEACHEMEN1KMT2A | |
| SCHEMBL23507476 | 0.79 | BCHE (0.63) | BACE1BCHEACHEMEN1KMT2A | |
| SCHEMBL12302951 | 0.78 | BCHE (0.71) | BACE1BCHEACHE | |
| SCHEMBL3141850 | 0.77 | ACHE (0.60) | BACE1BCHEACHEMEN1KMT2A | |
| SCHEMBL4903573 | 0.76 | CXCR4 (0.60) | CCR2 | |
| SCHEMBL27558591 | 0.75 | BCHE (0.62) | BACE1BCHEACHEMEN1KMT2A | |
| SCHEMBL27558592 | 0.75 | BCHE (0.62) | BACE1BCHEACHEMEN1KMT2A | |
| SCHEMBL27558721 | 0.75 | BCHE (0.62) | BACE1BCHEACHEMEN1KMT2A | |
| SCHEMBL10059136 | 0.74 | BCHE (0.61) | BACE1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069815-A1 | UREIDO-SUBSTITUTED CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUG | TEIJIN LIMITED (JP) | 2000-11-23 | — | — | WO | disclosed |