SCHEMBL4906513

SCHEMBL4906513

[O]C(=O)COc1ccccc1-c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.70
TDP1 Q9NUW8 3/20 0.70
LMNA P02545 5/20 0.60
MAPK1 P28482 4/20 0.60
HTT P42858 4/20 0.56
MAPT P10636 2/20 0.56
USP2 O75604 1/20 0.56
RXRA P19793 1/20 0.55
RXRB P28702 1/20 0.55
RXRG P48443 1/20 0.55
ALDH1A1 P00352 5/20 0.54
KDM4E B2RXH2 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.51
RAB9A P51151 1/20 0.51
PTGDR2 Q9Y5Y4 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1947848 0.87 L3MBTL1 (0.72) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL28416661 0.84 L3MBTL1 (0.68) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL4907668 0.82 KDM4E (0.59) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL7041403 0.81 L3MBTL1 (0.64) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL13444685 0.81 L3MBTL1 (0.64) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL14327977 0.81 L3MBTL1 (0.64) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL7806644 0.80 PTGDR2 (0.65) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL13444680 0.78 L3MBTL1 (0.60) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL7873889 0.78 PTPN1 (0.61) L3MBTL1TDP1LMNAMAPK1HTT
SCHEMBL3725265 0.78 ATM (0.68) L3MBTL1TDP1LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080107829-A1 Cellulose compound, cellulose film, optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-05-08 US disclosed