Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947848 | 0.93 | L3MBTL1 (0.72) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL30537993 | 0.83 | L3MBTL1 (0.59) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL19086322 | 0.81 | PTGDR2 (0.61) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL2442473 | 0.81 | L3MBTL1 (0.58) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL12147210 | 0.81 | PTGDR2 (0.60) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL29682135 | 0.80 | L3MBTL1 (0.80) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL340762 | 0.80 | L3MBTL1 (0.80) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL27688196 | 0.80 | L3MBTL1 (0.65) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 | |
| SCHEMBL4906513 | 0.80 | L3MBTL1 (0.70) | PTGDR2L3MBTL1TDP1SMN1; SMN2LMNA | |
| SCHEMBL27776102 | 0.80 | L3MBTL1 (0.52) | PTGDR2L3MBTL1TDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077929-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999061410-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |