Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.64 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907491 | 0.95 | CTSK (0.64) | CTSKACACBCTSLCTSBCTSS | |
| SCHEMBL4899347 | 0.94 | CTSK (0.65) | CTSKACACB | |
| SCHEMBL4900912 | 0.88 | CTSK (0.61) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4904030 | 0.88 | CTSK (0.61) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4905736 | 0.87 | CTSK (0.73) | CTSKCTSLCTSBCTSS | |
| SCHEMBL14260286 | 0.85 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4904858 | 0.83 | CTSK (0.58) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4910220 | 0.82 | CTSK (0.73) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4910161 | 0.81 | CTSK (0.73) | CTSKCTSLCTSBCTSS | |
| SCHEMBL5636933 | 0.81 | CTSK (0.63) | CTSKACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058333-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | CATALANO JOHN G | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058333-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | CTSK, CTSS, CTSE | CTSK 1/4885ACACB 370/4885CTSL 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.