SCHEMBL1107202

SCHEMBL1107202

CC(=O)NOC(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
MAPT P10636 3/20 0.68
KMT2A Q03164 2/20 0.68
POLB P06746 2/20 0.68
TSHR P16473 5/20 0.59
LMNA P02545 3/20 0.52
F2 P00734 1/20 0.52
CASP3 P42574 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
PKM P14618 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
SLC6A3 Q01959 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
TP53 P04637 1/20 0.44
NAPRT Q6XQN6 1/20 0.43
RECQL P46063 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645360 0.98 ALDH1A1 (0.66) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL4907232 0.85 ALDH1A1 (0.76) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL15317892 0.82 TDP1 (0.61) ALDH1A1MAPTKMT2APOLBLMNA
SCHEMBL7371030 0.82 ALDH1A1 (0.66) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL4398385 0.81 ALDH1A1 (0.59) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL8981662 0.81 ALDH1A1 (0.59) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL6269137 0.81 ALDH1A1 (0.70) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL28121355 0.81 ALDH1A1 (0.48) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL5809526 0.81 ALDH1A1 (1.00) ALDH1A1MAPTKMT2APOLBTSHR
SCHEMBL29102460 0.81 ALDH1A1 (0.70) ALDH1A1MAPTKMT2APOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140044684-A1 Methods And Compositions For Regulating Gene Expression CHILDREN'S MEDICAL CENTER CORPORATION (US) 2014-02-13 US claimed
CN-102574992-A Liquid crystalline polymer and molded article POLYPLASTICS CO 2012-07-11 CN claimed
US-20090304641-A1 Methods and Compositions for Regulating Gene Expression CHILDREN'S HOSPITAL BOSTON (US) 2009-12-10 US claimed
WO-2007047706-A2 METHODS AND COMPOSITIONS FOR REGULATING GENE EXPRESSION CHILDREN'S HOSPITAL (US) 2007-04-26 WO claimed
CN-1546473-A Aliphatic amino substituted indole quinoline derivatives, their preparation method and pharmaceutical application 中山大学 2004-11-17 CN claimed
CN-1083473-A New imidazolium compounds and pharmaceutical composition thereof SMITHKLINE BEECHAM CORP (US) 1994-03-09 CN claimed
EP-0117080-B1 SKIN TREATMENT COMPOSITION UNILEVER PLC (GB) 1992-04-08 EP claimed
US-20250129087-A1 SALT CRYSTALS INTRA-CELLULAR THERAPIES, INC. (US) 2025-04-24 US disclosed
US-12281079-B2 Quinoline derivatives, processes for their preparation and uses thereof for the treatment of cancer LEAD DISCOVERY CENTER GMBH (DE) 2025-04-22 US disclosed
EP-4472638-A2 SALT CRYSTALS Intra-Cellular Therapies, Inc. (US) 2024-12-11 EP disclosed
CN-119095589-A Formulations of plasma kallikrein inhibitors 卡尔维斯塔制药有限公司 2024-12-06 CN disclosed
CN-118255866-A Crystalline form of lanreotide salt, and preparation method and application thereof 西交利物浦大学 2024-06-28 CN disclosed
US-20240115593-A1 METHISOPRINOL COMPOSITIONS PATEL REENA (IN) 2024-04-11 US disclosed
WO-2003048136-A1 CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF MERCK & CO., INC. (US) 2003-06-12 WO disclosed
CN-1298404-A Inhibitors of phospholipase A2 GENETICS INST (US) 2001-06-06 CN disclosed
CN-1211574-A Process for preparing benzodiazepine derivatives DONG KOOK PHARM CO LTD (KR) 1999-03-24 CN disclosed
EP-0117080-B1 SKIN TREATMENT COMPOSITION UNILEVER PLC (GB) 1992-04-08 EP disclosed
EP-0196910-B1 Benzo[a]phenazine derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1991-01-02 EP disclosed
CN-85109752-A Preparation triterpenoid organic acid ester and the method that contains the hypolipidemic agents of this compounds 1986-12-17 CN disclosed
US-4254027-A ESPECIALLY FOR AROMATIC POLYESTERS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115593-A1 METHISOPRINOL COMPOSITIONS INMT, MIF, CHRM1 ALDH1A1 1349/4885MAPT 1175/4885KMT2A 2415/4885
US-12281079-B2 Quinoline derivatives, processes for their preparation and uses thereof for the treatment of cancer AVPR2, AVPR1A, VHL ALDH1A1 1304/4885MAPT 2941/4885KMT2A 426/4885
US-20250129087-A1 SALT CRYSTALS SLC28A1, REN, NT5C3B ALDH1A1 2041/4885MAPT 1114/4885KMT2A 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.