Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913227 | 0.87 | MAPT (0.40) | MAPTHTTGAADHFRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4899154 | 0.86 | MAPT (0.39) | MAPTHTTGAADHFRSMN1; SMN2 | |
| SCHEMBL4912381 | 0.85 | RPS6KB1 (0.37) | MAPTRPS6KB1GAAGFERSMN1; SMN2 | |
| SCHEMBL4901811 | 0.78 | KDM4E (0.38) | MAPTHTR3ACYP3A4HTR1ACYP2D6 | |
| SCHEMBL4908538 | 0.77 | HPGD (0.36) | TP53CYP1A2CYP2C19HTTGFER | |
| SCHEMBL4908143 | 0.77 | HTR3E (0.48) | MAPTHTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL4911304 | 0.77 | KDM4E (0.41) | MAPTHTR3ACYP3A4HTR1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL4901792 | 0.76 | HTR3E (0.47) | MAPTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4901771 | 0.76 | ALDH1A1 (0.53) | MAPTHTR2BLMNAALDH1A1RAB9A | |
| SCHEMBL4909293 | 0.75 | TYMP (0.37) | MAPTTP53CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | TYMP, HPRT1, IMPDH1 | MAPT 4400/4885RPS6KB1 757/4885HTR3E 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.