Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP1 | P63208 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 3/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913227 | 0.83 | MAPT (0.40) | ALDH1A1LMNAKMT2AMAPTPOLB | |
| Hydrochloric Acid SCHEMBL4899154 | 0.82 | MAPT (0.39) | ALDH1A1LMNAKMT2AMAPTPOLB | |
| SCHEMBL4905248 | 0.80 | LMNA (0.51) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL4910047 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL4905049 | 0.78 | ABCB1 (0.45) | ALDH1A1LMNAMEN1KMT2AHTR2B | |
| SCHEMBL4901811 | 0.76 | KDM4E (0.38) | ALDH1A1LMNAMEN1KMT2ASLC6A7 | |
| SCHEMBL4908538 | 0.76 | HPGD (0.36) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4904993 | 0.75 | CNR1 (0.41) | CKS1BSKP1SKP2KITPOLB | |
| Hydrochloric Acid SCHEMBL4926745 | 0.74 | NPC1 (0.48) | ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL4910144 | 0.74 | NR3C1 (0.45) | ALDH1A1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | claimed |
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | TYMP, HPRT1, IMPDH1 | ALDH1A1 191/4885CKS1B 1956/4885SKP1 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.