Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 3/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633584 | 0.85 | TRPV1 (0.54) | PLK1RARBTHRATHRBTRPV1 | |
| SCHEMBL4411275 | 0.78 | MAPT (0.53) | ESRRGRARBHDAC1MEN1NPC1 | |
| SCHEMBL547838 | 0.77 | KCNH2 (0.60) | PLK1ESRRGNPC1RAB9ALMNA | |
| SCHEMBL20968926 | 0.77 | ESRRG (0.51) | PLK1ESRRGRARBNR1H4HDAC3 | |
| SCHEMBL20968925 | 0.77 | ESRRG (0.51) | PLK1ESRRGRARBNR1H4HDAC3 | |
| SCHEMBL7302615 | 0.75 | NR1H4 (0.76) | PLK1ESRRGNR1H4HDAC3HDAC8 | |
| SCHEMBL10708524 | 0.74 | THRB (0.52) | PLK1ESRRGRARBNR1H4THRA | |
| SCHEMBL545445 | 0.73 | CYP4F2 (0.47) | TRPV1 | |
| SCHEMBL21448657 | 0.73 | TSHR (0.46) | PLK1ESRRGRARBNR1H4HDAC3 | |
| SCHEMBL8902478 | 0.73 | RARB (0.59) | PLK1RARBTHRATHRBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080026020-A1 | Cosmetic composition combining a C-glycoside derivative and an associative polymer | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080026020-A1 | Cosmetic composition combining a C-glycoside derivative and an associative polymer | UGCG, GLA, GANC | PLK1 2378/4885ESRRG 3443/4885RARB 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.