Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907793 | 1.00 | TSHR (0.53) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL4581662 | 0.86 | TSHR (0.53) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL2299143 | 0.86 | TSHR (0.53) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL11760497 | 0.85 | TDP1 (0.51) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL6727081 | 0.85 | TSHR (0.56) | TSHRL3MBTL1TDP1DTYMKCDC25B | |
| SCHEMBL28075649 | 0.84 | TSHR (0.45) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL11758012 | 0.81 | TDP1 (0.55) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL11669352 | 0.79 | CA1 (0.53) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL28037252 | 0.79 | TSHR (0.50) | TSHRL3MBTL1TDP1CA1CA2 | |
| SCHEMBL11756245 | 0.79 | TSHR (0.53) | TSHRL3MBTL1TDP1DTYMKCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188680-A1 | Process Improvement Using Solubility Characteristics | MALLINCKRODT INC. | 2008-08-07 | — | — | US | disclosed |
| EP-1866274-A2 | PROCESS IMPROVEMENT USING SOLUBILITY CHARACTERISTICS | MALLINCKRODT INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006093728-A2 | PROCESS IMPROVEMENT USING SOLUBILITY CHARACTERISTICS | MALLINCKRODT INC. (US) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188680-A1 | Process Improvement Using Solubility Characteristics | ADH5, ADH1A, ADH1C | TSHR 4615/4885L3MBTL1 4419/4885TDP1 2034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.