SCHEMBL490787

SCHEMBL490787

Cc1ccc(C2(C3(c4ccc(C)cc4C)N=C(c4ccccc4)C(c4ccccc4)=N3)N=C(c3ccccc3)C(c3ccccc3)=N2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 5/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
CHRM1 P11229 2/20 0.38
RAB9A P51151 5/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
NPC1 O15118 4/20 0.38
MAPT P10636 5/20 0.36
HPGD P15428 4/20 0.36
LMNA P02545 4/20 0.36
CASP3 P42574 2/20 0.36
SENP8 Q96LD8 2/20 0.36
SENP7 Q9BQF6 2/20 0.36
SENP6 Q9GZR1 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
PSMB5 P28074 3/20 0.36
POLB P06746 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81799 0.82 ALDH1A1 (0.38) KDM4EALDH1A1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL2494354 0.79 PSMB5 (0.40) KDM4EALDH1A1L3MBTL1CHRM1RAB9A
SCHEMBL8665808 0.76 CYP1A2 (0.45) KDM4EALDH1A1L3MBTL1HPGDTSHR
SCHEMBL11594968 0.76 ALDH1A1 (0.34) ALDH1A1L3MBTL1RAB9ASMN1; SMN2NPC1
SCHEMBL14973574 0.74 NPC1 (0.41) KDM4EALDH1A1L3MBTL1CHRM1RAB9A
SCHEMBL5841127 0.71 ALDH1A1 (0.40) KDM4EALDH1A1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL2496323 0.70 MEN1 (0.38) ALDH1A1L3MBTL1CHRM1RAB9ASMN1; SMN2
SCHEMBL80380 0.69 CHRM1 (0.41) ALDH1A1CHRM1RAB9ASMN1; SMN2NPC1
SCHEMBL1877506 0.69 TAAR1 (0.40) KDM4EALDH1A1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL491327 0.69 LMNA (0.39) KDM4ECHRM1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10113907-B2 Ultraviolet-sensing sheet, ultraviolet-sensing set, and ultraviolet-sensing method FUJIFILM CORPORATION (JP) 2018-10-30 US disclosed
US-20170131144-A1 ULTRAVIOLET-SENSING SHEET, ULTRAVIOLET-SENSING SET, AND ULTRAVIOLET-SENSING METHOD FUJIFILM CORPORATION (JP) 2017-05-11 US disclosed
US-9068082-B2 Colored curable composition and color filter FUJIFILM CORPORATION (JP) 2015-06-30 US disclosed
US-20150108086-A1 COLORED CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-04-23 US disclosed
US-8652759-B2 Processing of lithographic printing plates with a developer solution containing a hydrophilic polymer EASTMAN KODAK COMPANY (US) 2014-02-18 US disclosed
US-8632937-B2 UV-sensitive lithographic printing plate precursor with benzoxazole derivative and analogues thereof as sensitizer EASTMAN KODAK COMPANY (US) 2014-01-21 US disclosed
EP-1849600-B1 Bakeable radiation-sensitive elements with a high resistance to chemicals EASTMAN KODAK CO (US) 2013-12-11 EP disclosed
US-8507181-B2 Method for developing and sealing of lithographic printing plates KODAK (NEAR EAST) INC. 2013-08-13 US disclosed
US-8361701-B2 Method for making lithographic plates EASTMAN KODAK COMPANY (US) 2013-01-29 US disclosed
EP-2293144-B1 Method of drying lithographic printing plates after single-step-processing EASTMAN KODAK CO (US) 2012-11-07 EP disclosed
WO-2007009580-A2 PHOTOPOLYMER COMPOSITION SUITABLE FOR LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 2007-01-25 WO disclosed
US-20060154169-A1 Radiation-sensitive compositions comprising a 1,4-dihydropyridine sensitizer and imageable elements based thereon KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-07-13 US disclosed
US-20060063101-A1 Radiation-sensitive elements KODAK POLYCHROME GRAPHICS LLC (US) 2006-03-23 US disclosed
EP-1586006-A1 RADIATION-SENSITIVE ELEMENTS Kodak Polychrome Graphics GmbH (DE) 2005-10-19 EP disclosed
WO-2004111731-A1 RADIATION-SENSITIVE COMPOSITIONS COMPRISING A 1,4-DIHYDROPYRIDINE SENSITIZER AND IMAGEABLE ELEMENTS BASED THEREON KODAK POLYCHROME GRAPHICS GMBH (DE) 2004-12-23 WO disclosed
WO-2004049068-A1 RADIATION-SENSITIVE ELEMENTS KODAK POLYCHROME GRAPHICS GMBH (DE) 2004-06-10 WO disclosed
US-5866298-A Radiation sensitive composition for color filters JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1999-02-02 US disclosed
US-5792589-A ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-08-11 US disclosed
EP-0775941-A1 Radiation sensitive composition for color filters JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-05-28 EP disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed