Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727676 | 0.87 | TSHR (0.54) | TSHRCA1CA2CA9AKR1C3 | |
| SCHEMBL23003 | 0.87 | TSHR (0.79) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL27879975 | 0.86 | TSHR (0.58) | TSHRAKR1C3CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10692630 | 0.86 | TSHR (0.72) | TSHRCA1CA2CA9FOLH1 | |
| Acetic Acid SCHEMBL28245857 | 0.85 | TSHR (0.71) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL28370887 | 0.85 | TSHR (0.76) | TSHRCA1CA2CA9FOLH1 | |
| Ammonia Solution, Strong SCHEMBL27527756 | 0.85 | TSHR (0.76) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL4848573 | 0.85 | TSHR (0.53) | TSHRCA1CA2CA9AKR1C3 | |
| SCHEMBL9450042 | 0.85 | KDM4E (0.56) | TSHRCA1CA2CA9AKR1C3 | |
| SCHEMBL9644043 | 0.84 | ALDH1A1 (0.67) | TSHRAKR1C3FOLH1ALDH1A1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354359-B2 | Heat-sensitive adhesive agent and heat-sensitive adhesive sheet | RICOH COMPANY, LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-7470809-B2 | Process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |
| US-20080176012-A1 | Heat-sensitive adhesive agent and heat-sensitive adhesive sheet | RICOH COMPANY, LTD. (JP) | 2008-07-24 | — | — | US | disclosed |
| EP-1897925-A1 | Heat-sensitive adhesive agent and heat-sensitive adhesive sheet | Ricoh Company, Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |